Cell Biology, 4th Edition

Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods—from single cell RNA sequencing to second generation super resolution fluorescence microscopy—on advancing our understanding. 

SECTION I
Introduction to Cell Biology
1 Cells as the Basis of Life on Earth
2 Evolution of Life on Earth
SECTION II
Chemical and Physical Background
3 Molecules: Structures and Dynamics
4 Biophysical Principles
5 Macromolecular Assembly
6 Research Strategies
SECTION III
Chromatin, Chromosomes, and the Cell Nucleus
7 Chromosome Organization
8 DNA Packaging in Chromatin and Chromosomes
9 Nuclear Structure and Dynamics
SECTION IV
Central Dogma: From Gene to Protein
10 Gene Expression
11 Eukaryotic RNA Processing
12 Protein Synthesis and Folding
SECTION V
Membrane Structure and Function
13 Membrane Structure and Dynamics
14 Membrane Pumps
15 Membrane Carriers
16 Membrane Channels
17 Membrane Physiology
SECTION VI
Cellular Organelles and Membrane Trafficking
18 Posttranslational Targeting of Proteins
19 Mitochondria, Chloroplasts, Peroxisomes
20 Endoplasmic Reticulum
21 Mechanisms of Vesicular Transport
22 Secretory Membrane System and Golgi Apparatus
23 Endocytosis and the Endosomal Membrane System
24 Processing and Degradation of Cellular Components
SECTION VII
Signaling Mechanisms
25 Plasma Membrane Receptors
26 Protein Hardware for Signaling
27 Second Messengers
28 Integration of Signals
SECTION VIII
Cellular Adhesion and the Extracellular Matrix
29 Cells of the Extracellular Matrix and Immune Systems of Animals
30 Extracellular Matrix Molecules
31 Cellular Adhesion
32 Intercellular Junctions
33 Connective Tissues
SECTION IX
Cytoskeleton and Cellular Motility
34 Actin and Actin-Binding Proteins
35 Microtubules and Centrosomes
36 Intermediate Filaments
37 Motor Proteins
38 Intracellular Motility
39 Cellular Motility
40 Muscles
SECTION X
Cell Cycle
41 Introduction to the Cell Cycle
42 G1 Phase and Regulation of Cell Proliferation,
43 S Phase and DNA Replication
44 G2 Phase: Responses to DNA Damage and Control of Entry Into Mitosis
45 Mitosis
46 Cytokinesis
47 Meiosis
48 Cell Death
Cell SnapShots
Glossary
Index