Ryan's Retina

Through six outstanding and award-winning editions, Ryan’s Retina has offered unsurpassed coverage of this complex subspecialty―everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their knowledge and expertise to create the most comprehensive reference available on retina today.

• Features sweeping content updates, including new insights into the fundamental pathogenic mechanisms of age-related macular degeneration, advances in imaging including OCT angiography and intraoperative OCT, new therapeutics for retinal vascular disease and AMD, novel immune-based therapies for uveitis, and the latest in instrumentation and techniques for vitreo-retinal surgery. 
• Includes five new chapters covering Artificial Intelligence and Advanced Imaging Analysis, Pachychoroid Disease and Its Association with Polypoidal Choroidal Vasculopathy, Retinal Manifestations of Neurodegeneration, Microbiome and Retinal Disease, and OCT-Angiography. 
• Includes more than 50 video clips (35 new to this edition) highlighting the latest surgical techniques, imaging guidance, and coverage of complications of vitreoretinal surgery. New videos cover Scleral Inlay for Recurrent Optic Nerve Pit Masculopathy, Trauma with Contact Lens, Recurrent Retinal Detachment due to PVR, Asteroid Hyalosis, and many more.    
• Contains more than 2,000 high-quality images (700 new to this edition) including anatomical illustrations, clinical and surgical photographs, diagnostic imaging, decision trees, and graphs.   
• Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. 

• Prelims
  1      Fluorescein Angiography: Basic Principles and Interpretation
  1      Fluorescein Angiography: Basic Principles and Interpretation
  2      Clinical Applications of Diagnostic Indocyanine Green Angiography
  2      Clinical Applications of Diagnostic Indocyanine Green Angiography
  3      Optical Coherence Tomography
  3      Optical Coherence Tomography
  4      Optical Coherence Tomography Angiography (OCTA)
  4      Autofluorescence Imaging
  5      Autofluorescence Imaging
  5      Widefield Imaging
  6      Widefield Imaging
  6      Intraoperative OCT Imaging
  7      Advanced Imaging Technologies
  7      Advanced Imaging Technologies
  8      Artificial Intelligence and Advanced Imaging Analysis
  8      Advanced Image Analysis
  9      Clinical Electrophysiology
  9      Electrogenesis of the Electroretinogram
  10    Diagnostic Ophthalmic Ultrasound
  10    Clinical Electrophysiology
  11    Color Vision and Night Vision
  11    Diagnostic Ophthalmic Ultrasound
  12    Visual Acuity and Contrast Sensitivity
  12    Color Vision and Night Vision
  13    Visual Fields in Retinal Disease
  13    Visual Acuity and Contrast Sensitivity
  14    The Development of the Retina
  14    Visual Fields in Retinal Disease
  15    Function and Anatomy of the Mammalian Retina
  15    The Development of the Retina
  16    Structure and Function of Rod and Cone Photoreceptors
  16    Structure and Function of Rod and Cone Photoreceptors
  17    Cell Biology of the Retinal Pigment Epithelium
  17    Function and Anatomy of the Mammalian Retina
  18    Glial Cells of the Fovea
  18    Cell Biology of the Retinal Pigment Epithelium
  19    Retinal and Choroidal Vasculature: Retinal Oxygenation
  19    Cell Biology of Retinal Glia
  20    Mechanisms of Normal Retinal Adhesion
  20    Retinal and Choroidal Vasculature: Retinal Oxygenation
  21    Structure, Function, and Pathology of Bruch’s Membrane
  21    Mechanisms of Normal Retinal Adhesion
  22    Vitreous and Vitreoretinal Interface
  22    Structure, Function, and Pathology of Bruch’s Membrane
  23    Mechanisms of Oxidative Stress in Retinal Injury
  23    Vitreous and Vitreoretinal Interface
  24    Mechanisms of Endoplasmic Reticulum Stress in Retinal Disease
  24    Mechanisms of Oxidative Stress in Retinal Injury
  25    Cell Death, Apoptosis, and Autophagy in Retinal Injury
  25    Mechanisms of Endoplasmic Reticulum Stress in Retinal Disease
  26    Inflammation and Immune Responses In Retinal Health and Disease
  26    Cell Death, Apoptosis, and Autophagy in Retinal Injury
  27    Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis
  27    Blood-Retinal Barrier, Immune Privilege, and Autoimmunity
  27    "Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis "
  27    Inflammation and Immune Responses In Retinal Health and Disease
  28    Blood-Retinal Barrier, Immune Privilege, and Autoimmunity
  28    Cellular Effects of Detachment and Reattachment on the Neural Retina and the Retinal Pigment Epithelium
  28    "Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis "
  29    Cell Biology of Retinal Glia
  29    Structure, Function, and Pathology of Bruch’s Membrane
  29    Retinal and Choroidal Vasculature: Retinal Oxygenation
  29    Pathogenesis of Serous Detachment of the Retina and Pigment Epithelium
  29    Mechanisms of Macular Edema and Therapeutic Approaches
  29    Genetic Mechanisms of Retinal Disease
  29    Blood-Retinal Barrier, Immune Privilege, and Autoimmunity
  30    Cellular Effects of Detachment and Reattachment on the Neural Retina and the Retinal Pigment Epithelium
  30    Mechanisms of Macular Edema and Therapeutic Approaches
  31    Retinal Manifestation of Neurodegeneration: A Focus on Alzheimer's Disease
  31    Cellular Effects of Detachment and Reattachment on the Neural Retina and the Retinal Pigment Epithelium
  32    Genetic Mechanisms of Retinal Disease
  32    Pathogenesis of Serous Detachment of the Retina and Pigment Epithelium
  33    Mitochondrial Genetics of Retinal Disease
  33    Genetic Mechanisms of Retinal Disease
  34    Epigenetic Mechanisms of Retinal Disease
  34    Neuroprotection
  34    Mitochondrial Genetics of Retinal Disease
  35    Microbiome and Retinal Disease
  35    Epigenetic Mechanisms of Retinal Disease
  36    Electrogenesis of the Electroretinogram
  36    Advanced Image Analysis
  36    Intraoperative OCT Imaging
  36    Gene Therapy for Retinal Disease
  36    Macular Dystrophies
  36    Gene Therapy for Retinal Disease
  37    Stem Cells and Cellular Therapy
  37    Stem Cells and Cellular Therapy
  38    Nanomedicine in Ophthalmology
  38    Nanomedicine in Ophthalmology
  39    Neuroprotection
  39    Neuroprotection
  40    Drug Delivery
  40    Drug Delivery
  41    Retinal Laser Therapy: Biophysical Basis and Applications
  41    Diabetic Retinopathy: Genetics and Etiologic Mechanisms
  41    Retinal Laser Therapy: Biophysical Basis and Applications
  42    Macular Dystrophies
  42    Retinitis Pigmentosa and Allied Disorders
  43    Retinitis Pigmentosa and Allied Disorders
  43    Hereditary Vitreoretinal Degenerations
  44    The Epidemiology of Diabetic Retinopathy
  44    Proliferative Diabetic Retinopathy
  44    Abnormalities of Rod and Cone Function
  44    Macular Dystrophies
  45    Hereditary Vitreoretinal Degenerations
  45    Hereditary Choroidal Diseases
  46    Hereditary Choroidal Diseases
  46    Abnormalities of Cone and Rod Function
  47    Diabetic Retinopathy: Genetics and Etiologic Mechanisms
  47    The Epidemiology of Diabetic Retinopathy
  48    Diabetes Mellitus
  48    Diabetic Retinopathy: Genetics and Etiologic Mechanisms
  49    Nonproliferative Diabetic Retinopathy and Diabetic Macular Edema
  49    Medical Management of Diabetes Mellitus
  49    Medical Management of Diabetes Mellitus
  50    Proliferative Diabetic Retinopathy
  50    Nonproliferative Diabetic Retinopathy and Diabetic Macular Edema
  51    Telescreening for Diabetic Retinopathy
  51    Proliferative Diabetic Retinopathy
  52    Hypertension
  52     Hypertension
  53     Retinal Artery and Capillary  Occlusions
  53     Telescreening for Diabetic Retinopathy
  54     Acquired Retinal Macroaneurysms
  54     Retinal Artery Obstructions
  55     Telescreening for Retinopathy of Prematurity
  55     Branch Retinal Vein Occlusion
  55     Acquired Retinal Macroaneurysms
  56     Central Retinal Vein Occlusion
  56     Branch Vein Occlusion
  57     Macular Telangiectasia Type 2
  57     Central Retinal Vein Occlusion
  58     Coats Disease
  58     Macular Telangiectasia
  59     Hemoglobinopathies
  59     Coats Disease
  60     Radiation Retinopathy
  60     Hemoglobinopathies
  61     Ocular Ischemic Syndrome
  61     Radiation Retinopathy
  62     Systemic Coagulopathy Syndromes
  62     Ocular Ischemic Syndrome
  63     Pediatric Retinal Vascular Diseases Retinopathy of Prematurity
  63     Coagulopathies
  64     Epidemiology and Risk Factors for Age-Related Macular Degeneration
  64     Pediatric Retinal Vascular Diseases
  65     Pathogenetic Mechanisms in Age-Related Macular Degeneration
  65     Telescreening for Retinopathy of Prematurity
  66      Age-Related Macular Degeneration: Non-Neovascular AMD: Early, Intermediate, and Geographic Atrophic Stages
  66      Epidemiology and Risk Factors for Age-Related Macular Degeneration
  67      Neovascular Age-Related Macular Degeneration
  67      Pathogenetic Mechanisms in Age-Related Macular Degeneration
  68      Pharmacotherapy of Age-Related Macular Degeneration
  68      Age-Related Macular Degeneration: Non-neovascular Early AMD, Intermediate AMD, and Geographic Atrophy
  69      Pathologic Myopia
  69      Neovascular (Exudative or “Wet”) Age-Related Macular Degeneration
  70      Angioid Streaks
  70      Pharmacotherapy of Age-Related Macular Degeneration
  71      Ocular Histoplasmosis
  71      Myopic Macular Degeneration
  72      Pachychoroid Disease and Its Association with Polypoidal Choroidal Vasculopathy
  72      Angioid Streaks
  73      Central Serous Chorioretinopathy
  73      Ocular Histoplasmosis
  74      Uveal Effusion Syndrome and Hypotony Maculopathy
  74      Polypoidal Choroidal Vasculopathy
  75      Sympathetic Ophthalmia
  75      Central Serous Chorioretinopathy
  76      Vogt-Koyanagi-Harada Disease
  76      Uveal Effusion Syndrome and Hypotony Maculopathy
  77      White Spot Syndromes and Related Diseases
  77      Sympathetic Ophthalmia
  78      Autoimmune Retinopathies
  78      Vogt-Koyanagi-Harada Disease
  79      Sarcoidosis
  79      White Spot Syndromes and Related Diseases
  80      Intermediate Uveitis
  80      Autoimmune Retinopathies
  81      Rheumatic Diseases
  81      Sarcoidosis
  82      HIV-Associated Infections
  82      Intermediate Uveitis
  83      Mycobacterial Infections
  83      Rheumatic Diseases
  84      Eales Disease
  84      HIV-Associated Infections
  85      Spirochetal Infections
  85      Mycobacterial Infections
  86      Ocular Toxoplasmosis
  86      Eales Disease
  87      Helminthic Disease
  87      Spirochetal Infections
  88      Endogenous Endophthalmitis: Bacterial and Fungal
  88      Ocular Toxoplasmosis
  89      Acute Retinal Necrosis Syndrome
  89      Helminthic Disease
  90      Drug Toxicity of the Posterior Segment
  90      Endogenous Endophthalmitis: Bacterial and Fungal
  91      Photic Retinal Injuries: Mechanisms, Hazards, and Prevention
  91      Acute Retinal Necrosis Syndrome
  92      Traumatic Chorioretinopathies
  92      Drug Toxicity of the Posterior Segment
  93      Retinal and Choroidal Disorders in Pregnancy (Pregnancy-Related Diseases)
  93      Photic Retinal Injuries: Mechanisms, Hazards, and Prevention
  94      Optic Disc Anomalies, Drusen, Pits, Hypoplasia and Associated Retinal Pathology
  94      Traumatic Chorioretinopathies
  95      Retina-Related Clinical Trials: A Resource Bibliography
  95      Pregnancy-Related Diseases
  96      Pathogenetic Mechanisms of Retinal Detachment
  96      Optic Disc Anomalies, Pits, and Associated Serous Macular Detachment
  97      Nonrhegmatogenous Retinal Detachment
  97      Retina-Related Clinical Trials: A Resource Bibliography
  98      Degenerative Retinoschisis
  98       Pathogenetic Mechanisms of Retinal Detachment
  99       Pathogenesis of Proliferative Vitreoretinopathy
  99       Nonrhegmatogenous Retinal Detachment
  100     Pathophysiology of Ocular Trauma
  100     Senile Retinoschisis
  101     The Biomechanics of Scleral Buckles in the Treatment of Retinal Detachment
  101     Pathogenesis of Proliferative Vitreoretinopathy
  102     Techniques of Scleral Buckling
  102     Pathophysiology of Ocular Trauma
  103     Principles and Techniques of Vitreoretinal Surgery
  103     The Effects and Action of Scleral Buckles in the Treatment of Retinal Detachment
  104     Intraoperative OCT Imaging
  104     Techniques of Scleral Buckling
  105     Primary Vitrectomy in Rhegmatogenous Retinal Detachment
  105     Principles and Techniques of Vitreoretinal Surgery
  106     Pneumatic Retinopexy
  106     Primary Vitrectomy in Rhegmatogenous Retinal Detachment
  107     Special Adjuncts to Treatment
  107     Pneumatic Retinopexy
  108     Optimal Procedures for Retinal Detachment Repair
  108     Special Adjuncts to Treatment
  109     Prevention of Retinal Detachment
  109     Optimal Procedures for Retinal Detachment Repair
  110     Proliferative Vitreoretinopathy
  110     Prevention of Retinal Detachment
  111     Retinotomies and Retinectomies
  111     Proliferative Vitreoretinopathy
  112     Giant Retinal Tear
  112     Retinotomies and Retinectomies
  113     Surgery for Ocular Trauma: Principles and Techniques of Treatment
  113     360 Degree Macular Translocation
  113     Surgical Management of Choroidal Neovascularization and Subretinal Hemorrhage
  113     Giant Retinal Tear
  114     Surgery for Proliferative Diabetic Retinopathy
  114     Surgery for Ocular Trauma: Principles and Techniques of Treatment
  115     Management of Combined Inflammatory and Rhegmatogenous Retinal Detachment
  115     Surgery for Proliferative Diabetic Retinopathy
  116     High Myopia and the Vitreoretinal Complications
  116     Management of Combined Inflammatory and Rhegmatogenous Retinal Detachment
  117     Surgical Management of Retinopathy of Prematurity
  117     High Myopia and the Vitreoretinal Complications
  118     Surgery for Pediatric Vitreoretinal Disorders
  118     Surgical Management of Retinopathy of Prematurity
  119     Epiretinal Membranes, Vitreoretinal Traction, Cystoid Macular Edema, and Submacular Hemorrhage
  119     Surgery for Pediatric Vitreoretinal Disorders
  120     Macular Hole
  120     Epiretinal Membranes, Vitreoretinal Traction and Cystoid Macular Edema
  121     Retinal Pigment Epithelium and Choroid Translocation in Patients with Age-Related Macular Degeneration
  121     Macular Hole
  122     Infectious Endophthalmitis
  122     Surgical Management of Choroidal Neovascularization and Subretinal Hemorrhage
  123     Diagnostic and Therapeutic Vitrectomy for Uveitis
  123     360 Degree Macular Translocation
  124     Vitreous, Retinal, and Choroidal Biopsy
  124     Retinal Pigment Epithelium and Choroid Translocation in Patients with Age-Related Macular Degeneration
  125     Transplantation Frontiers
  125     Infectious Endophthalmitis
  126     Artificial Vision
  126     Remote Effects of Cancer on the Retina
  126     Diagnostic and Therapeutic Vitrectomy for Uveitis
  127     Pharmacology During Surgery
  127     Vitreous, Retinal, and Choroidal Biopsy
  128     Complications in Vitreoretinal Surgery
  128     Transplantation Frontiers
  129     Retinoblastoma
  129     Artificial Vision
  130     Cavernous Hemangioma
  130     Epidemiology of Posterior Uveal Melanoma
  130     Pharmacology During Surgery
  131     Capillary Hemangioblastoma of the Retina and von Hippel-Lindau Disease
  131     Complications in Vitreoretinal Surgery
  132     Tuberous Sclerosis and the Eye
  132     Retinoblastoma
  133     Phakomatoses
  133     Cavernous Hemangioma
  134     Retinal Metastases
  134     Capillary Hemangioblastoma of the Retina and von Hippel-Lindau Disease
  135    Tuberous Sclerosis and the Eye
  135     Remote Effects of Cancer: Paraneoplastic Autoimmune Retinopathies
  136     Optic Disc Melanocytoma
  136     Phakomatoses
  137     Congenital Hypertrophy of the Retinal Pigment Epithelium
  137     Retinal Metastases
  138     Combined Hamartoma of the Retinal Pigment Epithelium and Retina
  138     Remote Effects of Cancer on the Retina
  139     Choroidal Nevi
  139     Laser Treatment of Choroidal Melanoma
  139     Melanocytoma of the Optic Disc
  140     Epidemiology of Posterior Uveal Melanoma
  140     Congenital Hypertrophy of the Retinal Pigment Epithelium
  141     Prognosis of Posterior Uveal Melanoma
  141     Combined Hamartoma of the Retinal Pigment Epithelium and Retina
  142     Molecular Genetics of Choroidal Melanoma
  142     Choroidal Nevi
  143     Pathology of Choroidal Melanoma
  143     Epidemiology of Posterior Uveal Melanoma
  144     Overview of Management of Posterior Uveal Melanoma
  144     Prognosis of Posterior Uveal Melanoma
  145     Enucleation for Choroidal Melanomas
  145     Molecular Genetics of Choroidal Melanoma
  146     Brachytherapy for Choroidal Melanoma
  146     Pathology of Choroidal Melanoma
  147     Charged-Particle Irradiation of Uveal Melanoma
  147     Overview of Management of Posterior Uveal Melanoma
  148     Surgical Resection of Choroidal Melanoma
  148     Enucleation for Choroidal Melanomas
  149     Laser Treatment of Choroidal Melanoma
  149     Brachytherapy for Choroidal Melanoma
  150     Systemic Evaluation and Management of Patients with Metastatic Uveal Melanoma
  150     Charged-Particle Irradiation of Uveal Melanoma
  151     Collaborative Ocular Melanoma Study
  151     Surgical Resection of Choroidal Melanoma
  152     Choroidal Metastases
  152     Laser Treatment of Choroidal Melanoma
  153     Choroidal Osteoma
  153     Systemic Evaluation and Management of Patients with Uveal Melanoma
  154     Circumscribed Choroidal Hemangioma
  154     Collaborative Ocular Melanoma Study
  155     Miscellaneous Uveal Tumors
  155     Choroidal Metastases
  156     Leukemias and Lymphomas
  156     Choroidal Osteoma
  157     Primary Vitreoretinal Lymphoma
  157     Circumscribed Choroidal Hemangioma
             Index
  158     Miscellaneous Uveal Tumors
  159     Leukemias and Lymphomas
  160     Primary Vitreoretinal Lymphoma