Hematology: A Pathophysiologic Approach

Gain a foundational understanding of complex hematology concepts with this thoroughly revised text. Hematology: A Pathophysiologic Approach, 2nd Edition, a volume in the Mosby Physiology Series, explains the fundamentals of this multi-faceted area in a clear and concise manner. It offers masterful explanations of hematopoiesis, immunology, hemostasis, hemoglobinopathy, metabolic disorders, genetics, and neoplasia from S. David Hudnall, MD, Professor Emeritus of Pathology and Laboratory Medicine at Yale University School of Medicine. Prof. Hudnall, who has practiced laboratory hematology and hematopathology for more than 30 years, has taught the principles of hematology to thousands of pre-medical undergraduates and medical students. Rich, clinically oriented coverage from cover to cover makes this text an ideal, problem-based way to learn about this complex subject.

• Offers an accessible yet thorough understanding of hematolymphoid physiology and pathophysiology, helping you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, and end-of-chapter review questions. 

   

• Clearly explains interrelationships between the diverse factors that can give rise to disease. 

   

• Covers a wide range of subjects, including platelets and coagulation,  transfusion medicine, cytotoxic chemotherapy, infections, the immune system, and bone marrow transplantation.   

   

• Shows how hematologic disorders are evaluated through blood counting, histopathology, immunohistochemistry, cytogenetics, and coagulation testing. 

   

• Features 150 full-color photomicrographs to help you visualize a wide spectrum of hematologic pathology. 

   

• An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. 

1. BRIEF OVERVIEW OF THE HEMATOLYMPHOID SYSTEM
2. HEMATOPOIESIS
3. ERYTHROPOIESIS AND OXYGEN TRANSPORT
4. IRON, HEME, AND HEMOGLOBIN
5. HEMOGLOBINOPATHY
6. RED BLOOD CELL METABOLISM AND ENZYME DEFECTS
7. HEMOLYTIC ANEMIA
8. APLASTIC ANEMIA AND RELATED DISORDERS
9. MEGALOBLASTIC ANEMIA
10. MYELOID CELLS
11. IMMUNE SYSTEM AND RELATED DISORDERS
12. GENETIC BASIS OF HEMATOPOIETIC NEOPLASIA
13. LEUKEMIA AND RELATED DISORDERS
14. LYMPHOMA AND RELATED DISORDERS
15. BLOOD COAGULATION
16. PLATELETS
17. BENIGN CONDITIONS OF LYMPHOID ORGANS
18. BLOOD TRANSFUSION AND STEM CELL TRANSPLANTATION
19. CANCER CHEMOTHERAPY
APPENDIX A ANSWERS TO REVIEW QUESTIONS
APPENDIX B COMPLETE BLOOD COUNT
APPENDIX C SOME USEFUL IMMUNOPHENOTYPIC MARKERS FOR HEMATOLOGIC DIAGNOSIS