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9780443250088
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This volume in the Diagnostic Pathology series is an ideal point-of-care resource for practitioners at all levels of experience and training. Covering the full range of solid organ transplantation (SOT) of the kidney, liver, heart, lung, pancreas, intestine, and more, it provides a current understanding of transplant immunology and pathology to help ensure accurate diagnosis for optimal clinical management. Richly illustrated and easy to use, Diagnostic Pathology: Transplant Pathology, third edition, is a visually stunning, one-stop reference for practicing pathologists, transplant practitioners, and students of organ transplantation. | ||
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SECTION 1: IMMUNOLOGY 4 Immune Response in Organ Transplantation Roshini Sarah Abraham, PhD, D(ABMLI) 8 Regulatory Immune Cells and Transplant Tolerance Roshini Sarah Abraham, PhD, D(ABMLI) 14 Viral Infections and Immune Response Roshini Sarah Abraham, PhD, D(ABMLI) 20 Genetics of Complement Defects Associated with Atypical HUS and TMA Roshini Sarah Abraham, PhD, D(ABMLI) 24 Laboratory-Based Immune Monitoring in Organ Transplantation Sanya J. Thomas, MD and Roshini Sarah Abraham, PhD, D(ABMLI) 30 Immune Manipulation and Accommodation: Introduction to Xenogenic Transplantation Roshini Sarah Abraham, PhD, D(ABMLI) 34 Graft Vs. Host Disease in Solid Organ Transplantation Roshini Sarah Abraham, PhD, D(ABMLI) and Sanya J. Thomas, MD SECTION 2: HLA TESTING 40 Human Leukocyte Antigen System Manish J. Gandhi, MD 42 Histocompatibility Testing Manish J. Gandhi, MD 44 Transplantation and HLA Manish J. Gandhi, MD 48 ABO Blood Group Antigens and Transplantation Manish J. Gandhi, MD 50 Apheresis and Transplantation Manish J. Gandhi, MD 52 HLA and Transfusion Manish J. Gandhi, MD SECTION 3: IMMUNOSUPPRESSIVE DRUGS 56 Mechanism of Action of Immunosuppressive Drugs Loralie Langman, PhD and Florian Lemaitre, PharmaD, PhD 58 Therapeutic Drug Monitoring in Transplant Patients Loralie Langman, PhD and Florian Lemaitre, PharmaD, PhD 62 History of Immunosuppression Drugs in Transplantation Loralie Langman, PhD and Florian Lemaitre, PharmaD, PhD SECTION 4: KIDNEY TRANSPLANTATION 66 History of Kidney Transplantation Lynn D. Cornell, MD 68 Pathologic Classification of Renal Allograft Diseases Robert B. Colvin, MD 70 Examination of End-Stage Kidney Shane Meehan, MB, BCh 76 Evaluation of the End-Stage Kidney Shane Meehan, MB, BCh 82 Evaluation of Allograft Kidney Lynn D. Cornell, MD and Evan Farkash, MD, PhD 88 Evaluation of Donor Kidney Lynn D. Cornell, MD and Evan Farkash, MD, PhD 94 Evaluation of Transplant Nephrectomy Shane Meehan, MB, BCh and Evan Farkash, MD, PhD 98 Evaluation of Fibrosis A. Brad Farris, III, MD, MBA 102 Protocol Biopsies Lynn D. Cornell, MD and Evan Farkash, MD, PhD 106 Accommodation Lynn D. Cornell, MD 108 Tolerance Robert B. Colvin, MD SURGICAL COMPLICATIONS 112 Acute Allograft Ischemia A. Brad Farris, III, MD, MBA 116 Size Mismatch Allograft Injury Anthony Chang, MD and Yael K. Heher, MD, MPH, FRCP(C) 118 Urine Leak A. Brad Farris, III, MD, MBA 119 Lymphocele A. Brad Farris, III, MD, MBA 120 Multinucleated Endotheliopathy Jonathan Zuckerman, MD, PhD 124 Transplant Renal Artery Stenosis A. Brad Farris, III, MD, MBA 126 Tranplant Renal Artery or Vein Thrombosis A. Brad Farris, III, MD, MBA 128 Kidney Xenografts Ivy A. Rosales, MD 132 Chronic Antibody-Mediated Rejection Lynn D. Cornell, MD and Michael Mengel, MD ALLOGRAF REJECTION 144 Hyperacute Rejection Lynn D. Cornell, MD and Michael Mengel, MD 148 Acute T-Cell-Mediated Rejection Lynn D. Cornell, MD and Michael Mengel, MD 158 Chronic T-Cell-Mediated Rejection Lynn D. Cornell, MD and Michael Mengel, MD 162 Acute Antibody-Mediated Rejection Lynn D. Cornell, MD and Michael Mengel, MD 170 Transcript Analysis of Renal Transplant Biopsies Michael Mengel, MD and R. Neal Smith, MD, PhD RECURRENT AND DE NOVO DISEASES 174 Diseases That Recur in Allografts Anthony Chang, MD, Lynn D. Cornell, MD, and R. Neal Smith, MD, PhD 180 De Novo Focal Segmental Glomerulosclerosis Anthony Chang, MD and Astrid Weins, MD, PhD 182 De Novo Membranous Nephropathy Anthony Chang, MD 186 Anti-GBM Disease in Alport Syndrome Anthony Chang, MD and R. Neal Smith, MD, PhD 188 Chimerism Transition Syndrome A. Brad Farris, III, MD, MBA 190 Late Posttransplant Histology Lynn D. Cornell, MD KIDNEY PATHOLOGY OF RECIPIENTS OF OTHER TRANSPLANTS 192 Kidney Diseases in Nonrenal Transplant Recipients Robert B. Colvin, MD 196 Graft-vs.-Host Glomerulopathies Anthony Chang, MD and Yael K. Heher, MD, MPH, FRCP(C) DRUG TOXICITIES 198 Calcineurin Inhibitor Toxicity Shane Meehan, MB, BCh 204 mTOR Inhibitor Toxicity Lynn D. Cornell, MD INFECTIONS 206 Acute Pyelonephritis Neeraja Kambham, MD 214 Polyomavirus Nephritis Anthony Chang, MD and Evan Farkash, MD, PhD 222 Adenovirus Infection Anthony Chang, MD and R. Neal Smith, MD, PhD 224 Cytomegalovirus Infection Anthony Chang, MD and R. Neal Smith, MD, PhD 226 Mucormycosis Anthony Chang, MD 228 Histoplasmosis Anthony Chang, MD 229 Candidiasis Anthony Chang, MD 230 Cryptococcosis Anthony Chang, MD 231 Aspergillosis Anthony Chang, MD 232 Coccidioidomycosis Anthony Chang, MD 233 Paracoccidioidomycosis Anthony Chang, MD 234 Microsporidiosis Robert B. Colvin, MD 236 Tuberculosis Neeraja Kambham, MD 238 Malakoplakia Neeraja Kambham, MD 242 Nocardiosis Neeraja Kambham, MD SECTION 5: LIVER TRANSPLANTATION 246 Pathologic Classification of Liver Allograft Diseases John Hart, MD and Lindsay Alpert, MD 248 Gross Evaluation of Failed Native Liver John Hart, MD and Lindsay Alpert, MD 252 Evaluation of Failed Liver Allograft John Hart, MD and Lindsay Alpert, MD 254 Evaluation of the Donor Liver John Hart, MD 258 History of Liver Transplantation Anthony Chang, MD and John Hart, MD POSTTRANSPLANT SURGICAL COMPLICATIONS 260 Preservation Injury Hanlin L. Wang, MD, PhD 262 Hepatic Artery Thrombosis Lisa Yerian, MD 264 Portal Vein Thrombosis Lisa Yerian, MD 266 Bile Duct Stricture, Leak, Sludge, Biloma Hanlin L. Wang, MD, PhD 268 Hepatic Venous Outflow Obstruction Hanlin L. Wang, MD, PhD 272 Hyperperfusion Syndrome Hanlin L. Wang, MD, PhD ALLOGRAFT REJECTION 274 T-Cell-Mediated Rejection, Liver Lisa Yerian, MD 278 Antibody-Mediated Rejection, Liver Hanlin L. Wang, MD, PhD, Robert B. Colvin, MD, and Richard Masia, MD, PhD 282 Chronic (Ductopenic) Rejection Matthew M. Yeh, MD, PhD RECURRENT DISEASES IN LIVER ALLOGRAFT 284 Recurrent Hepatitis B Virus Lindsay Alpert, MD 286 Recurrent Hepatitis C Virus Lindsay Alpert, MD 290 Fibrosing Cholestatic HBV or HCV Hepatitis Lindsay Alpert, MD 292 Recurrent Autoimmune Hepatitis Lindsay Alpert, MD 294 Recurrent Primary Biliary Cholangitis Lindsay Alpert, MD 296 Recurrent Primary Sclerosing Cholangitis Lindsay Alpert, MD 298 Recurrent Fatty Liver Disease Lindsay Alpert, MD INFECTIONS 300 Cytomegalovirus Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG 302 Herpes Simplex Virus Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG 304 Adenovirus, Liver Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG 306 Hepatitis E Virus Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG 308 Epstein-Barr Virus, Liver Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG 312 Fungal Infections, Liver Maria Westerhoff, MD and Joseph Ahn, MD, MS, FACG LATE-GRAFT DYSFUNCTION 314 Plasma Cell-Rich Rejection Lisa Yerian, MD 316 Graft-vs.-Host Disease, Liver Lisa Yerian, MD SECTION 6: HEART TRANSPLANTATION 320 Pathologic Classification of Cardiac Allograft Diseases Aliya N. Husain, MD 322 Evaluation of Failed Native and Transplanted Heart Jennifer Pogoriler, MD, PhD 324 History of Heart Transplantation Aliya N. Husain, MD and Aarti Sharma, MD EVALUATION OF EXPLANTED HEART 326 Ischemic Heart Disease Aliya N. Husain, MD and Aarti Sharma, MD 330 Dilated Cardiomyopathy Jennifer Pogoriler, MD, PhD 334 Hypertrophic Cardiomyopathy Jennifer Pogoriler, MD, PhD and Aliya N. Husain, MD 338 Congenital Heart Disease Jennifer Pogoriler, MD, PhD and Aliya N. Husain, MD 342 Sarcoidosis, Heart Aliya N. Husain, MD and Aarti Sharma, MD 344 Arrhythmogenic Right Ventricular Cardiomyopathy Jennifer Pogoriler, MD, PhD and Aliya N. Husain, MD 348 Other Causes of End-Stage Heart Disease Jennifer Pogoriler, MD, PhD and Aliya N. Husain, MD ALLOGRAFT REJECTION 354 Acute Cellular Rejection, Heart Aliya N. Husain, MD and Jennifer Pogoriler, MD, PhD 358 Antibody-Mediated Rejection, Heart Aliya N. Husain, MD and Aarti Sharma, MD 360 Chronic Allograft Vasculopathy, Heart Aliya N. Husain, MD and Aarti Sharma, MD NONINFECTIOUS LESIONS 362 Quilty Lesions Aliya N. Husain, MD and Aarti Sharma, MD 364 Site of Previous Biopsy Aliya N. Husain, MD and Vijayalakshmi Ananthanarayanan, MD INFECTIONS 366 Myocarditis Jennifer Pogoriler, MD, PhD and Aliya N. Husain, MD SECTION 7: LUNG TRANSPLANTATION 374 Pathologic Classification of Lung Allograft Diseases Aliya N. Husain, MD and Aarti Sharma, MD 376 Examination of Native and Transplanted Lungs Aliya N. Husain, MD 378 History of Lung Transplantation Aliya N. Husain, MD and Aarti Sharma, MD EVALUATION OF FAILED NATIVE LUNG 380 Emphysema Aliya N. Husain, MD 382 Cystic Fibrosis Aliya N. Husain, MD 384 Idiopathic Pulmonary Fibrosis Aliya N. Husain, MD and Aarti Sharma, MD 386 Connective Tissue Disease-Associated Lung Disease Ilyssa O. Gordon, MD, PhD and Aliya N. Husain, MD 388 Sarcoidosis, Lung Aliya N. Husain, MD 390 Pulmonary Arterial Hypertension Aliya N. Husain, MD and Aarti Sharma, MD 392 Other Causes of End-Stage Lung Disease Aliya N. Husain, MD and Aarti Sharma, MD SURGICAL COMPLICATIONS 396 Surgical Aspects and Complications, Lung Aliya N. Husain, MD and Aarti Sharma, MD ALLOGRAFT REJECTION 398 Pathologic Classification of Rejection Aliya N. Husain, MD and Aarti Sharma, MD 400 Antibody-Mediated Rejection, Lung Aliya N. Husain, MD and Ilyssa O. Gordon, MD, PhD 402 Acute Cellular Rejection, Grade A Aliya N. Husain, MD 404 Acute Cellular Rejection, Grade B Aliya N. Husain, MD 406 Chronic Allograft Dysfunction, Lung Aliya N. Husain, MD NONINFECTIOUS LESIONS 408 Organizing Pneumonia Aliya N. Husain, MD 410 Microaspiration Aliya N. Husain, MD INFECTIONS 412 Bacterial Infections Aliya N. Husain, MD and Ilyssa O. Gordon, MD, PhD 414 Viral Infections Aliya N. Husain, MD and Aarti Sharma, MD 418 Fungal Infections, Lung Aliya N. Husain, MD SECTION 8: INTESTINAL TRANSPLANTATION 424 Pathologic Classification of Intestinal Allograft Diseases Sarangarajan Ranganathan, MD 426 Indications and Evaluation of Explant Sarangarajan Ranganathan, MD 430 Reperfusion Injury Sarangarajan Ranganathan, MD 434 History of Intestinal and Multivisceral Transplantation Sarangarajan Ranganathan, MD ALLOGRAFT REJECTION/IMMUNOLOGICAL INJURY 436 Acute Antibody-Mediated Rejection, Intestine Sarangarajan Ranganathan, MD 440 Acute Cellular Rejection, Intestine Sarangarajan Ranganathan, MD 448 Chronic Rejection, Intestine Sarangarajan Ranganathan, MD 452 Stomach Rejection Sarangarajan Ranganathan, MD 456 Colon Rejection Sarangarajan Ranganathan, MD 460 Graft-vs.-Host Disease, Intestine Sarangarajan Ranganathan, MD INFECTIONS 464 Bacterial and Fungal Infections Sarangarajan Ranganathan, MD 468 Adenovirus, Intestine Sarangarajan Ranganathan, MD 472 Rotavirus, Cytomegalovirus, and Herpes Simplex Virus Sarangarajan Ranganathan, MD 476 Epstein-Barr Virus, Intestine Sarangarajan Ranganathan, MD SECTION 9: PANCREAS TRANSPLANTATION 484 Pathologic Classification of Pancreas Allograft Diseases Surya V. Seshan, MD and Billie S. Fyfe, MD 486 Clinical Considerations in Pancreas Transplant Evaluation Surya V. Seshan, MD and Billie S. Fyfe, MD 492 History of Pancreas Transplantation Surya V. Seshan, MD and Billie S. Fyfe, MD 494 History of Islet Transplantation Piotr Witkowski, MD, PhD SURGICAL COMPLICATIONS 498 Surgical Aspects and Complications, Pancreas Surya V. Seshan, MD and Billie S. Fyfe, MD ALLOGRAF REJECTION 504 Acute Cellular Rejection, Pancreas Surya V. Seshan, MD, Billie S. Fyfe, MD, and Erika R. Bracamonte, MD 508 Antibody-Mediated Rejection, Pancreas Surya V. Seshan, MD and Billie S. Fyfe, MD 512 Chronic Allograft Rejection/Graft Sclerosis Surya V. Seshan, MD, Billie S. Fyfe, MD, and Erika R. Bracamonte, MD GRAFT DYSFUNCTION 514 Recurrent Diabetes Mellitus Surya V. Seshan, MD and Billie S. Fyfe, MD 518 Islet Cell Toxicity and Islet Amyloid Deposition Surya V. Seshan, MD and Billie S. Fyfe, MD INFECTIONS 520 Intraabdominal and Opportunistic Infections Surya V. Seshan, MD and Billie S. Fyfe, MD SECTION 10: VASCULARIZED COMPOSITE ALLOTRANSPLANTATION 528 History of Vascularized Composite Allotransplantation Linda Cendales, MD ALLOGRAFT REJECTION 530 Acute T-Cell- and Antibody-Mediated Rejection A. Brad Farris, III, MD, MBA, Ivy A. Rosales, MD, and Robert B. Colvin, MD 538 Chronic Rejection A. Brad Farris, III, MD, MBA, Robert B. Colvin, MD, and Ivy A. Rosales, MD SECTION 11: POSTTRANSPLANT NEOPLASTIC DISORDERS 542 Posttransplant Lymphoproliferative Diseases A. Brad Farris, III, MD, MBA |
ISBN | 9780443250088 |
Basım Yılı | 2024 |
Basım Sayısı | 3 |
Sayfa Sayısı | 624 |
Kitap Dili | İngilizce |
Yazar(lar) | Anthony Chang |